Lead author Dr. Nita Forouhi, of the Medical Research Council Epidemiology Unit at the University of Cambridge in the United Kingdom, and colleagues report their findings in the journal BMC Medicine.

Cardiovascular disease (CVD) refers to conditions that affect the heart and blood vessels, including stroke, heart attack, and heart disease.

Heart disease is the leading cause of death for both men and women in the United States, killing around 610,000 people annually. Heart attack affects around 735,000 Americans each year, while around 800,000 people are affected by stroke.

Adopting a healthy diet is considered key for reducing the risk of CVD, and numerous studies have suggested the Mediterranean diet fits the bill.

A study published in the European Heart Journal earlier this year, for example, found older adults who adhered to the Mediterranean diet were at lower risk of heart attack, stroke, and cardiovascular death than those who followed a Western diet.

The Mediterranean diet is typically high in plant-based foods - such as fruits, vegetables, whole grains, and nuts - and low in red meats and unhealthy fats. It also incorporates regular consumption of fish and poultry, and red wine is acceptable in moderation.

For their study, Dr. Forouhi and team set out to investigate how adhering to a Mediterranean diet affects the risk of developing CVD, as well as what proportion of CVD cases and deaths might be prevented in the U.K. as a result of adherence to the diet.

CVD risk up to 16 percent lower with the Mediterranean diet
The team analyzed data from 23,902 healthy adults who were a part of the EPIC-Norfolk Study - a multi-center cohort study of more than 30,000 British adults that mainly looks at the link between diet, lifestyle, and cancer.

As part of the study, participants completed food frequency questionnaires, which the researchers analyzed to determine adherence to the Mediterranean diet. They did so using a 15-point score based on guidelines from the Mediterranean Diet Foundation.

Over an average follow-up period of 12-17 years, the researchers identified 7,606 new cases of CVD among the participants, as well as 1,714 CVD deaths.

Compared with participants with low adherence to the Mediterranean diet, the researchers found that subjects with higher adherence to the diet were 6-16 percent less likely to develop CVD.

Applying their results to the U.K. population, the team estimated that if healthy Britons adhered to the Mediterranean diet, around 3.9 percent of new-onset CVD cases and 12.5 percent of CVD deaths could be prevented.

"If our findings are broadly representative of the overall U.K. population, then we can assume that higher level of adherence to the Mediterranean diet could have significant impact in lowering the cardiovascular disease burden in the U.K.," notes Dr. Forouhi.

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental condition characterized by poor attention, impulsive behavior, and hyperactivity.

According to the Centers for Disease Control and Prevention (CDC), as of 2011, approximately 11 percent of children aged between 4 and 17 in the United States have received a diagnosis of ADHD, making it one of the most common neurodevelopmental disorders in childhood.

Although the precise causes of ADHD are unclear, previous research has suggested that a poor diet may play a role. Some studies have also indicated that healthful diets could help to prevent or treat ADHD, though other research has challenged this theory.

For the new study, team leader María Izquierdo Pulido, of the Faculty of Pharmacy and Food Sciences of the University of Barcelona in Spain, and colleagues investigated whether a Mediterranean diet might be associated with lower ADHD diagnosis.

"To our knowledge, there are no studies that examined the potential relationship between adherence to the Mediterranean diet and ADHD," the authors note.

ADHD diagnosis likelier with low adherence to Mediterranean diet

The Mediterranean diet is typically high in fruits, vegetables, fish, whole grains, nuts, and legumes, and low in red meats, eggs, dairy products, and sweets.

A Mediterranean diet is considered by many as the optimal diet for good health, with studies linking this eating pattern to reduced risk of heart diseaseAlzheimer's disease, and some types of cancer.

To determine whether this diet may be effective against ADHD, Pulido and team analyzed the data of 60 children and adolescents aged between 6 and 16 who had been diagnosed with ADHD. These children were matched by age and sex to 60 children without ADHD.

The dietary patterns of the two groups were assessed using food frequency questionnaires, and the team used the KIDMED test to calculate the children's adherence to a Mediterranean diet.

Compared with children who had high adherence to a Mediterranean diet, those with a low adherence were more likely to have received a diagnosis of ADHD, the researchers report.

Furthermore, the team identified a higher prevalence of ADHD among children who consumed high amounts of candy and sugary drinks, but low amounts of fatty fish.

While the researchers say that their study cannot conclude that a Mediterranean diet protects against ADHD, they say that their findings do indicate that poor dietary patterns may be linked to the disorder.

Friday, 30 December 2016 17:54

Hold Campgain My Doctor Pharmacist

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What is the difference between a cold and flu?

Symptoms of flu

People with flu normally feel very unwell for two or three days, and will continue to experience symptoms for around another five days. After that, you may feel tired and run down for a further two or three weeks.

The most common symptoms of flu are:

•  a sudden fever (above 38°C or 100.4°F)

•  headache

•  chills

•  runny or stuffy nose

•  tiredness

•  aching muscles

•  dry cough

•  sore throat

Symptoms of a cold

Symptoms of a cold can include:

•  runny or blocked nose

•  sneezing

•  sore throat

•  cough


Treating flu

Most people recover effectively from flu by resting at home, although you should see your GP if you:

•  are aged 65 or over

•  are pregnant

•  have heart disease, diabetes, asthma, lung disease or another long-term medical condition

•  have a weakened immune system

•  have a very high fever, together with abdominal or chest pain or an unusually severe headache

If none of these apply to you, your body should recover from flu of its own accord. You should get lots of rest, stay warm, and drink plenty of water. You can treat the symptoms of flu by taking:

•  paracetamol to lower your fever

•  ibuprofen for muscle aches

•  cough syrup if you have a cough

•  a decongestant if you have a blocked nose

Treating a cold

Resting and taking care of yourself are usually enough to cure a cold. You should:

•  drink plenty of fluids

•  rest your body

•  eat healthily

You can treat the symptoms of a cold to help you feel better, but this will not make you recover sooner.

You could:

•  take cough syrup or throat lozenges

•  take painkillers such as ibuprofen, paracetamol or aspirin

•  gargle salt water, which may help ease a sore throat and nasal congestion

•  take decongestants to help with a blocked nose. These can either be taken orally or as a spray in your nose.

Friday, 30 December 2016 17:47

The Challenge of Chronic Pain

Chronic pain is a major health care challenge. Approximately 20% of the world’s population has an on-going pain problem, many of whom are poorly served with currently available treatment modalities. Because pain affects the elderly disproportionally, it is becoming an increasingly important and expensive problem in our aging population. The growing use of neurotoxic drugs to treat cancer and infectious diseases, and the recognition of sexual dimorphism in both pain mechanisms and the clinical presentation of pain syndromes further emphasize the need to better understand the underlying mechanisms of acute and chronic pain, so that improved therapies can be offered to patients.

The second Challenge of Chronic Pain conference will discuss recent discoveries and current challenges in pain research, with a focus on translating basic research insights into new therapies. Advances in our understanding of peripheral and central pain mechanisms, pathways and processes will be highlighted. We will explore the clinical landscape of chronic pain and pain syndromes, the innovative approaches in target validation in animal and human studies, and their translation into novel therapeutic interventions.

This meeting is aimed at scientists, clinicians, and those working in industry or on translational research, interested in understanding chronic pain and improving the process from mechanism to therapy.


Source: https://coursesandconferences.wellcomegenomecampus.org

Publication date: Jan 19, 2017 12:19 PM

Start: Mar 16, 2017 09:00 AM 
End: Mar 16, 2017 04:30 PM

Location: Kennedy Lecture Theatre, ICH, 30 Guilford Street, London WC1N 1EH

The 6th Annual UCL Cardiovascular Science Symposium 2017 will cover various aspects of cutting edge cardiovascular science from early career UCL researchers. There will be a focus on cross-disciplinary, new horizons and future frontiers of cardiovascular research. There will also be a moderated poster session and a presentation regarding grant funding from the British Heart Foundation

Refreshments will be provided throughout the day and spaces are limited, registration will be on a first come, first served basis to UCL/H staff, students, invited guests and sponsors. Please contact Sophie Oliver-Styller before booking a place, if you are a non-UCL/H member wishing to attend. We would be grateful if you could please confirm your attendance as soon as possible by registering on Eventbrite. The deadline for abstracts is midnight on the 23rd February 2017.
Organisers: Professor Aroon Hingorani (UCL Institute for Cardiovascular Science) , Dr Ines Pineda Torra (UCL Division of Medicine), Professor John Greenwood (Institute of Ophthalmology)

For enquires and abstract forms, please contact This email address is being protected from spambots. You need JavaScript enabled to view it. 

Source: http://www.ucl.ac.uk

Friday, 30 December 2016 17:43

DoM Research Retreat 2017

Publication date: Sep 14, 2016 11:41 AM

Start: May 11, 2017 08:30 AM 
End: May 11, 2017 05:00 PM

Location: Marriott Hotel West India Quay

The 2017 Division of Medicine Research Retreat will take place on Thursday 11th May 2017. The venue will be the Marriott Hotel, West India Quay, 22 Hertsmere Road, London E14 4ED

Lunch will be provided, as will tea, coffee, soft drinks and biscuits throughout the day. The Division will finance this event, so all you need to do is to turn up. The day will commence with Registration, tea/coffee at 8.30 a.m.  and will close in the afternoon with a Reception. 

Spaces are limited so it will be on a first come, first served basis.  I would be grateful if you could please confirm your attendance as soon as possible by registering below. 

Source: http://www.ucl.ac.uk

Publication date: Dec 16, 2015 03:56 PM

Start: Jan 18, 2016 09:30 AM 
End: Jan 18, 2016 05:00 PM

Location: Kennedy Lecture Theatre, Institute of Child Health, 30 Guilford Street, WC1N 1EH

18th January 2016, 9.30am to 5pm 

Kennedy Lecture Theatre | Institute for Child Health | 30 Guilford Street | London | WC1N 1EH.

This event is jointly organised by the Institute of Cardiovascular Science in collaboration with the Division of Medicine and the Institute of Ophthalmology. This is the 5th Annual UCL Symposium on Cardiovascular Science. It will present the best cardiovascular science from across UCL, with a focus on new horizons in cardiovascular science and on heart failure research from basic science to the clinic. 

The symposium will feature: 

  • Cutting edge cardiovascular science from early career researchers 
  • Moderated poster sessions 
  • The award of prizes for best posters and best talk by an early career researcher 
  • A moderated panel discussion on “How best to advance Heart Failure Research at UCL”. 

The symposium will be followed by a drinks reception (with food provided) from 5pm. 

All UCL cardiovascular scientists are strongly encouraged to present their work at this meeting. The deadline for abstract submissions (for posters) is Friday 8th January 2016. An abstract submission form is available from This email address is being protected from spambots. You need JavaScript enabled to view it.

Please register your attendance at this Symposium no later than Monday 11th January 2016. To register for the Symposium or to submit an abstract, please email This email address is being protected from spambots. You need JavaScript enabled to view it.

Source: http://www.ucl.ac.uk/

Friday, 30 December 2016 17:40

White bread

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most people know that white bread is a diet don’t: One of the easiest swaps you can make for a major health boost is ditching refined flour in favor of whole wheat. But it’s not just that loaf of Wonder Bread that you need to watch out for. The basket of rolls delivered to the table when dining out, the French baguette you grab on your way home to accompany dinner, your Saturday-morning bagel ritual, and Friday pizza night all come with a side of less-than-desirable health risks. Here are five unpleasant reasons to nix the bread basket:

Little nutritional value. Yes, food is delicious, but at the end of the day we are eating for one reason: to nourish our bodies. And white bread made with refined flour fails to accomplish this goal. “When a grain is refined, such as in the making of flour for white bread, the outermost and innermost layers of the grain are removed. This removes the fiber and some (25 percent) protein, leaving behind the starch,” says Erin Palinski-Wade, RD, author of Belly Fat Diet For Dummies. You may see "enriched flour" on the label. While this flour has had some nutrients like B vitamins and iron added back in after the refining process, it’s still lower in fiber and protein than whole-wheat flour. Opting for whole-grain varieties carries with it a dose of healthy fiber and more protein, adding a nutritional boost to meals.

Erratic blood-sugar levels. “Since it's low in the fiber and protein that helps to slow digestion, white bread is digested and absorbed rapidly. This leads to blood sugar's rising quickly,” says Palinski-Wade. This spike — and subsequent crash — in blood sugar not only leads to irritability, but will leave you headed to the vending machine for a pick-me-up.

Increased risk of type-2 diabetes. “When blood sugar elevates rapidly, excess insulin is released into the bloodstream to push the sugar into the cell,” says Palinski-Wade. “When this occurs on a regular basis, cells become more insulin resistant, making it harder over time to control blood-glucose (sugar) levels. Research published in 2010 in the American Journal of Clinical Nutrition supports this, finding that people who consumed several servings of whole grains per day — and limited intake of refined grains — had less of a type of fat that increases risk of type 2 diabetes.

Weight gain. After eating refined carbohydrates like white bread, the surplus of sugar in your bloodstream — unless immediately utilized for activity — tends to be stored as fat in the body. Plus, the blood-sugar crash will leave you hungry soon after ingesting, so you'll be reaching for another snack. “Rapid digestion can increase hunger and cravings, leading to a lack of satiety after eating, which may result in increased caloric intake at the end of the day,” says Palinski-Wade.

Symptoms of depression. It may taste good going down, but that white bread can negatively affect your mood. New research published in the June 2015 American Journal of Clinical Nutrition found a link between the consumption of refined carbohydrates — like white bread — and depression in post-menopausal women. The same hormonal response that causes blood-sugar levels to drop can also cause mood swings, fatigue, and other symptoms of depression.

Black bread calorie

Brown Bread Calories and Nutrition per Serving (1 Serving=1 Med Slice/34g)

Calories 74
Protein 2.9
Carbohydrate 15.1
Fat 0.7
Fibre 1.2
Alcohol 0

Friday, 30 December 2016 17:40

The Top 10 Fat Burning Foods List

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  1. Green Tea
    Make green tea your drink of choice to quench that thirst, satisfy your minimum daily fluid intake while at the same time burning those calories. Green tea contains the anti-oxidant EGCG which works to burn calories throughout the whole day.

    Also keep in mind the added benefit of green tea replacing those drinks laden with sugars and the host of other health benefits such as the anti cancer and cholesterol maintenance properties.
  2. Whole grain bread
    The fibre content of wholegrain bread is high along with the nutritional benefits of the seeds within. Wholegrain toast makes for a satisfying and low GI breakfast and wholegrain bread is excellent for sandwiches or as the side carbohydrate for a meal like soup.

    Important to note is that brown bread does not mean whole grain. Some brown bread can contain colourings to achieve its brown appearance.
  3. Salmon
    It is packed with good fats which are conducive to weight loss. It is super easy to prepare and a cost effective, satisfying meal with a plate of vegetables and brown rice for example. A steak of salmon can be covered in a bowl and cooked in the microwave for 2-3 minutes. Try the condiment Chermoula if you can get your hands on it. Delicious!
  4. Garlic and Onions
    Yes we know, garlic and onions are two foods not one. We will bunch them together because of their ease of use and common combination and addition to foods. 
    Minerals and oils inside garlic and onions help to break down fat and increase the metabolism. 

    Onions and/or garlic can be utilized in every meal. 
  5. Broccoli
    If you can appreciate the green flavour of broccoli you have yourself a low calorie, zero fat vegetable that can accompany any meal. Broccoli boasts a great deal of fibre and a host of other health benefits in your daily diet. It is a great accompaniment in almost any meal and filling.
  6. Berries
    Berries are high in nutrients including antioxidants. When you buy them frozen their freshness is locked in and they can be kept for some time and used in a variety of ways. In summer thaw a few berries in your mouth. Just like ice cubes, only tastier. Add them to your oatmeal, cereal, low fat ice cream or yoghurt.
  7. Lean Chicken
    Versatile, tasty, filling and high in protein. Chicken can be used in a variety of dishes for lunch and dinner.
  8. Yoghurt
    It is high in protein, great as a part of breakfast, dessert and a tasty snack. Low fat yoghurt is a great way to get your daily dose of dairy and can be transformed into a delicious meal with the addition of fruits or cereal.
  9. Brown Rice
    Once you go brown you’ll never want to go back to white. It has substance and is covered in fibre. The nutty taste and texture of brown rice goes beautifully with your meats (such as lean chicken) and vegetables and is very filling.

    Be sure to drink plenty of water when you have something as fibre rich in your diet as brown rice. 

10. Oranges
Not just rich in Fibre, the high vitamin C content of oranges is conducive to fat burning. Vitamin C promotes the production of Carnitine in the body which oxidizes fatty acids (breaks them down/burns fat).

Preferably eat your oranges fresh rather then in supplement form or juice. The fruit is highest in fiber and a filling and sweet satisfying end to meals.

Publication date: Feb 22, 2016 02:39 PM

Start: Feb 26, 2016 01:00 PM 
End: Feb 26, 2016 02:00 PM

Location: 2nd floor Seminar Room, Rayne Building

 Internal Speaker Series

Dr Anna David, Reader in Obstetrics and Maternal Fetal Medicine, Institute for Women's Health, Faculty of Population Health Sciences

“Therapeutic manipulation of angiogenic factors for treatment of fetal growth restriction”

Host: Professor John Martin


Source: http://www.ucl.ac.uk

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